Is aboriginal food less allergenic? A study on the IgE-binding capacity of egg white and yolk from modern and ancient chicken breeds investigated in a cohort of hen’s egg allergic children
نویسندگان
چکیده
Results In our cohort, 48% of patients were sensitized to egg white and yolk, while 52% were reacting to egg white exclusively. In allergen microarray, Gal d 1 and 2 were identified as major allergens for all patients, whereas Gal d 3-5 displayed high sensitization prevalence only in patients reacting to both egg components. Mean egg white-specific IgE was significantly higher in patients displaying additional sensitization to yolk compared to yolk-negative individuals (6.31 μg/ml and 1.53 μg/ml, respectively). Eggs from ancient chicken breeds demonstrated reduced egg white/yolk ratios compared to those from conventional laying hen hybrids but did not differ in their allergen composition as determined by mass spectrometry. Accordingly, we observed no significant differences in IgE-binding and basophil mediator release assays comparing egg white and yolk from different chicken breeds.
منابع مشابه
Is Aboriginal Food Less Allergenic? Comparing IgE-Reactivity of Eggs from Modern and Ancient Chicken Breeds in a Cohort of Allergic Children
BACKGROUND Hen's egg allergy ranks among the most frequent primary food allergies in children. We aimed to investigate sensitization profiles of egg allergic patients and compare in vitro IgE reactivities of eggs from ancient chicken breeds (Araucana and Maran) with those from conventional laying hen hybrids. METHODOLOGY Egg allergic children (n = 25) were subjected to skin prick test, double...
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